Table 6

Kinetic parameters describing the hydroxylation of TLB in human liver microsomes incubated with or without BSA

BSAUncorrectedCorrected6-c
KmVmax6-aVmax/Km6-bKmuVmax6-aVmax/Kmu6-b
% μM μM
0181  ± 20444  ± 252.4
0.25113  ± 176-d 452  ± 354.036  ± 56-e 391  ± 2910.9

Values are mean ± S.D. from three determinations.

  • 6-a  The unit ofVmax is pmol/min/mg protein.

  • 6-b  The unit ofVmax/Km is μl/min/mg protein.

  • 6-c  Corrected forfu.

  • 6-dp < 0.05 compared with the control value (BSA = 0%).

  • 6-ep < 0.05 compared with the corresponding value of each BSA concentration.