Table 2

Comparison of NMR data obtained for authentic standard of 4-hydroxyatomoxetine oxalate and the major metabolite in microsomal preparations

Atom Type	4′-Hydroxytomoxetine		Isolated Metabolite
Atom Type	δC	δH	δC	δH
1-NH-		8.08		5.84
2-CH₂-	45.67	2.93	47.75	2.64
3-CH₂-	34.64	2.06; 2.18	37.76	1.9; 2.09
4-CH-	76.70	5.26	77.70	5.23
5-C	141.36		142.47
6,10-CH	126.02	7.34	126.16	7.36
7,9-CH	128.53	7.34	128.40	7.33
8-CH	127.69	7.26	127.41	7.25
1′-C	147.94		148.50
2′-C	127.37		127.60
3′-CH	117.43	6.52	117.50	6.54
4′-C	150.93		150.55
5′-CH	112.29	6.34	112.31	6.36
6′-CH	114.44	6.51	114.43	6.52
2′-CH₃	16.37	2.14	16.12	2.17
1-CH₃	32.98	2.50	35.62	2.32