Table 2

Mean recovery of radioactivity in urine and feces following i.v. (25 mg) and p.o. (100 mg.) administration of [¹⁴C]etoricoxib (100 μCi) to six healthy male subjects

Sample	Interval	Percent of Dose Recovered^2-a
		Oral		i.v.
		Mean	S.D.	Mean	S.D.
	h
Urine	0–2	2.96	0.98	2.40	1.03
	2–4	6.33	1.48	5.11	3.47
	4–6	3.62	1.51	5.71	2.92
	6–9	5.53	2.09	4.78	1.64
	9–12	5.39	1.99	7.91	2.44
	12–18	3.85	2.27	4.59	3.22
	18–24	5.62	4.54	4.35	1.86
	24–36	7.83	1.23	11.20	4.66
	36–48	5.14	1.35	7.23	3.31
	48–72	5.83	1.42	8.19	3.13
	72–96	4.16	1.24	3.58	1.87
	96–120	2.17	1.66	2.70	1.57
	120–168	1.58	2.04	2.34	2.47
	Sub Total	60.0	5.50	70.1	12.1
Feces	0–24	2.17	2.04	1.00	1.63
	24–48	3.92	2.64	5.40	4.42
	48–72	7.48	4.62	6.84	3.81
	72–96	2.55	2.18	3.31	2.62
	96–120	1.82	1.55	1.53	1.59
	120–144	0.79	0.75	1.83	2.27
	144–168	0.71	0.83	0.73	0.53
	168–192	0.56	0.93	0.33	0.34
	192–216	0.13	0.23	0.07	0.06
	216–240	0.15	0.21	0.25	0.53
	Sub Total	20.3	7.84	20.4	6.59
Urine and Feces	Total	80.3	7.10	90.4	13.3

↵2-a Data represent mean and S.D. (n = 6 subjects).