Covariation of mRNA expression of CYP3As and PXR with exclusion of an outlier with respect to CYP3A4 and PXR mRNA
Variables | Spearman Rank Correlation (rs) | 95% CI | p Value |
|---|---|---|---|
| CYP3A4 mRNA versus CYP3A5 mRNA | 0.66 | 0.45-0.80 | <0.0001 |
| CYP3A4 mRNA versus CYP3A43 mRNA | 0.87 | 0.78-0.93 | <0.0001 |
| CYP3A5 mRNA versus CYP3A43 mRNA | 0.73 | 0.56-0.84 | <0.0001 |
| PXR mRNA versus CYP3A4 mRNA | 0.66 | 0.45-0.80 | <0.0001 |
| PXR mRNA versus CYP3A5 mRNA | 0.63 | 0.42-0.78 | <0.0001 |
| PXR mRNA versus CYP3A43 mRNA | 0.65 | 0.44-0.79 | <0.0001 |