Species | t1/2,z | CLint | CLhep | ||
---|---|---|---|---|---|
h | l/h/106 cells | l/h/kg | l/h/kg | ||
Rat | 0.34 ± 0.03 | 0.93 ± 0.17 | 4.5 ± 0.8 | 2.2 ± 0.2 | |
Dog | 1.2 ± 0.8 | 0.57 ± 0.27 | 2.2 ± 1.0 | 0.94 ± 0.31 | |
Monkey | 0.48 ± 0.01 | 0.54 ± 0.13 | 2.1 ± 0.3 | 1.2 ± 0.1 | |
Human | 4.2 ± 2.3 | 0.18 ± 0.09 | 0.56 ± 0.26 | 0.32 ± 0.13 |