TABLE 2

Urinary recovery

Values are μmol with percentage of dose recovered calculated in parentheses.




0-2 h

2-6 h

6-12 h

12-24 h

24-48 h

48-72 h

Overall (0-72 h)
Achiral Results
MDMA 9.0 ± 4.1 28.0 ± 11.0 22.9 ± 12.4 31.4 ± 16.6 20.0 ± 13.5 3.4 ± 5.2 114.2 ± 38.1
(1.7) (5.4) (4.4) (6.1) (3.9) (0.6) (22.0)
MDA 0.2 ± 0.2 1.3 ± 0.5 1.6 ± 1.0 2.9 ± 1.4 2.8 ± 1.6 0.7 ± 1.0 9.5 ± 4.24
(0.04) (0.3) (0.3) (0.6) (0.5) (0.1) (1.8)
HMMA 7.7 ± 4.0 16.2 ± 5.3 14.3 ± 11.2 14.0 ± 7.8 13.8 ± 7.2 8.4 ± 4.8 74.4 ± 32.7
(1.5) (3.1) (2.8) (2.7) (2.7) (1.4) (14.1)
Chiral Results
(R)-MDMA 5.6 ± 2.6 18.9 ± 7.0 13.9 ± 6.1 24.8 ± 14.5 17.1 ± 11.8 3.5 ± 5.8 83.1 ± 28.9
(1.1) (3.6) (2.7) (4.8) (3.3) (0.6) (16.0)
(S)-MDMA 4.6 ± 2.3 12.8 ± 4.7 7.3 ± 2.7 7.2 ± 4.1 2.3 ± 1.3 2.3 ± 4.2 36.1 ± 10.5
(0.9) (2.5) (1.4) (1.4) (0.4) (0.4) (7.0)
(1)-MDA 0.03 ± 0.02 0.2 ± 0.1 0.5 ± 0.3 1.4 ± 0.6 2.0 ± 1.4 0.6 ± 0.7 4.7 ± 2.7
(0.01) (0.05) (0.09) (0.3) (0.4) (0.1) (1.0)
(2)-MDA 0.2 ± 0.1 1.0 ± 0.4 1.2 ± 0.8 1.9 ± 1.1 0.8 ± 0.5 0.05 ± 0.07 4.0 ± 2.5
(0.04) (0.2) (0.2) (0.4) (0.2) (0.01) (1.1)
(R)-HHMA 3.3 ± 2.1 6.3 ± 4.9 8.8 ± 9.0 10.2 ± 10.2 13.3 ± 7.4 3.8 ± 3.8 45.2 ± 25.5
(0.6) (1.2) (1.7) (2.0) (2.6) (0.6) (8.7)
(S)-HHMA 8.9 ± 3.2 14.6 ± 9.5 15.0 ± 9.1 12.5 ± 12.0 5.0 ± 5.1 1.1 ± 1.5 57.0 ± 24.2
(1.7) (2.8) (2.9) (2.4) (1.0) (0.2) (11.0)
(R)-HMMA 5.2 ± 5.1 8.8 ± 3.8 6.3 ± 4.3 9.9 ± 5.4 10.5 ± 7.7 3.5 ± 3.8 44.2 ± 23.8
(1.0) (1.7) (1.2) (1.9) (2.0) (0.6) (8.5)
(S)-HMMA 3.9 ± 1.8 8.8 ± 3.8 5.9 ± 3.7 5.6 ± 2.7 0.9 ± 0.9 0.2 ± 0.1 25.2 ± 9.9

(0.8)
(1.7)
(1.1)
(1.1)
(0.2)
(0.02)
(4.9)
  • (1)-MDA, first eluted MDA enantiomer; (2)-MDA, second eluted MDA enantiomer.