Time period | Urine | n | Feces | n | Total | n |
---|---|---|---|---|---|---|
h | % dose | % dose | % dose | |||
0 to 48 | 10.6 ± 1.5 | 4 | 16.1 ± 12.4 | 4 | 26.7 ± 12.5 | 4 |
0 to 168a | 13.2 ± 1.6 | 4 | 66.9 ± 4.5a | 4 | 80.2 ± 5.0a | 4 |
0 to 264b | N.D. |
| 67.8 ± 5.4b | 3 | 81.1 ± 4.9b | 3 |
N.D., Not determined.
↵ a Excreta were collected completely from n = 4 subjects and were measured over the period of 0 to 168 h. The last feces sample within the planned study was collected at 154 h
↵ b To follow the excretion beyond 168 h, additional feces samples were collected in three subjects in the period of 208 to 264 h. No feces were collected in the period of 154 to 208 h. Thus, the tabulated observation period of 0 to 264 h was not covered completely