TABLE 1
Solved equations on the biliary excretion clearance, metabolic clearance, and total hepatic clearance by Sirianni and Pang ( 1997 )
These equations are reduced in complexity when CLinflux = CLefflux ≫ QL and CLint,met and CLint,sec. QL is the plasma flow rate to the liver.
Clerance Terms | Solutions Depending on Whether CLinflux and CLefflux Are Rapid at Basolateral Membrane | ||
|---|---|---|---|
| CLinflux and CLefflux Are Comparable to QL, CLint,met, and CLint,sec | CLinflux = CLefflux ≫ QL, CLint,met, and CLint,sec | ||
| CLliver,ex |
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| CLliver,met |
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| CLliver,tot |
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