Effect of drug induction of UGTs on MPAG and AcMPAG formation by rat liver microsomes
Results are means of duplicate measurements.
Formation Rate | |||
|---|---|---|---|
| MPAG | AcMPAG | ||
| nmol/mg/min | |||
| Control rats | 2.46 ± 0.08 | 0.18 ± 0.03 | |
| 3-Methylcholanthrene-induced rats | 4.37 ± 0.24 | 0.11 ± 0.03 | |
| Phenobarbital-induced rats | 2.02 ± 0.02 | 0.27 ± 0.05 | |