The expression level of Mrp2 protein in rat and dog liver
Mrp2 protein expression levels in rat and dog livers were quantified by Western blot analysis using respective MBP fusion protein as a standard. Results represent the mean ± S.D. of triplicate determinations. The alkaline phosphatase (ALP) activities in the crude membrane fraction and liver homogenate are shown.
Rat | Dog | |
|---|---|---|
| Mrp2 protein expression (pmol Mrp2 molecules/mg protein) | 22.5 ± 0.75 | < 2.23 |
| Ratio | 1.00 | < 0.10 |
| ALP activity | ||
| Crude membrane/Homogenate (nmol/min/mg protein) | 38.9/6.2 | 67.2/10.4 |
| Enrichment | 6.27 | 6.46 |