TABLE 2

Genomic DNA fragments used for DNase I sensitivity assay


Digest

Target Gene

Fragment Location

Fragment Size
bp
BamHI/HpaI CYP3A4 –4729 to +890 5619
BamHI/HpaI CYP3A5 –5782 to +1622 7404
BamHI/HpaI CYP3A7 –2050 to +2415 4465
HindIII/ClaI PXR –5124 to +208 5332
SfiI/BclI
GAPDH
–6431 to +156
6587