TABLE 3

C24T G1249 (Val417Ile) and C3972T variants of the MRP2 gene in the population and in terms and preterms (preterm data in parentheses)


Genotype

Number

Position

Identified Frequency

Expected Frequency

Allele

Allelic Frequency
%
C/C 37 -24 63.8 67.2 C 0.82
20 (17) 62.5 (65.4) 65.6 (68.9) 0.81 (0.83)
C/T 21 -24 36.2 29.5 T 0.18
12 (9) 37.5 (34.6) 30.8 (28.2) 0.19 (0.17)
T/T 0 -24 0 3.2
0 0 (0) 3.6 (2.9)
G/G 37 1249 63.7 60.8 G 0.78
16 (21) 50.0 (80.8) 49.0 (74.0) 0.70 (0.86)
G/A 16 1249 29.3 34.3 A 0.22
13 (3) 40.6 (11.5) 42.0 (22.4) 0.30 (0.13)
A/A 5 1240 8.6 4.8
3 (2) 9.4 (7.7) 9.0 (1.8)
C/C 22 3972 39.7 37.4 C 0.62
11 (11) 34.4 (46.1) 35.2 (40.3) 0.59 (0.65)
C/T 27 3972 46.6 47.6 T 0.38
16 (11) 50 (42.3) 48.4 (45.5) 0.41 (0.35)
T/T 9 3972 15.5 15.0

5 (4)

15.6 (15.4)
16.8 (12.2)