Kinetic parameters of metabolism for genistein, daidzein, formononetin, glycitein, biochanin A, and prunetin by rat ileal microsomes
Isoflavone | Genistein | Daidzein | Formononetin | Glycitein | Biochanin A | Prunetin | |
|---|---|---|---|---|---|---|---|
| Ileum | Vmax1 (nmol/min/mg) | 1.4 | 0.6 | 0.6 | 1.4 | 0.4 | 0.8 |
| Km1 (μM) | 8.3 | 5.5 | 9.0 | 2.1 | 7.1 | 1.8 | |
| Vmax1/Km1 (ml/min/mg) | 0.2 | 0.1 | 0.1 | 0.7 | 0.1 | 0.4 | |
| Vmax2 (biphasic) (nmol/min/mg) | 0.04 | 0.2 | |||||
| Km2 (μM) | 8.0 | 0.4 | |||||
| R 2 | 1.0 | 1.0 | 1.0 | 1.0 | 0.9 | 1.0 | |
|
| AIC | -22.0 | -45.0 | -30.7 | -35.7 | -28.0 | -42.0 |