Retention time (tR) and MS spectra of Ber and its metabolites
tR (min) | MS Spectra | |
|---|---|---|
| Ber | 7.0 | 336, 321 |
| M1 (berberrubine) | 6.9 | 322, 307 |
| M2 (thalifendine) | 5.8 | 322, 307 |
| M3 (demethyleneberberine) | 4.9 | 324, 309 |
| M4 (jatrorrhizine) | 6.2 | 338, 323 |
| M1, M2-glucuronide | 4.3, 5.7 | 498, 322, 307 |
| M3-glucuronide | 5.1 | 500, 324, 309 |
| M4-glucuronide | 5.0 | 514, 338, 323 |