TABLE 2

Mean percentages of circulating metabolites of erlotinib in humans 2 h after a single 100-mg oral dose of [14C]erlotinib (n = 4)


Metabolite

Percentage of Radioactivity
M6 1.6 ± 0.8
M11 4.2 ± 2.3
M14 5.4 ± 1.2
M16 0.7 ± 0.6
Erlotinib 82.8 ± 4.6
Total
94.7 ± 2.5