TABLE 1

Nonspecific binding of trifluoperazine to HLMs and HEK293 cell lysate


[TFP]

Fraction Unbound (fuinc)a
HLMs (0.1 mg/ml)
HEK293 Cell Lysate (0.25 mg/ml)
10 μM 0.21 0.20
30 μM 0.26 N.D.
60 μM 0.42 0.44
100 μM 0.49 0.50
200 μM
0.59
0.57
  • N.D., not determined

  • a Each value represents the mean from duplicate samples.