Mean derived kinetic parameters for LTG N2-glucuronidation by human liver microsomes in the presence of hecogenin, with and without BSA
S50 | Vmax1 | n | |
|---|---|---|---|
| μM | pmol/min/mg | ||
| Without BSA | |||
| Mean | 1848 | 235 | 0.74 |
| S.D. | 256 | 29 | 0.04 |
| Range | 783–2283 | 155–286 | 0.69–0.87 |
| With BSA | |||
| Mean | 382 | 156 | 0.71 |
| S.D. | 81 | 18 | 0.01 |
| Range | 223–690 | 106–212 | 0.68–0.74 |