Brain distribution of [3H]cyclosporin A after intravenous administration
The data are expressed as mean ± S.D. of 4∼5 rats.
n | Kp,brain | CLapp,br | |
|---|---|---|---|
| μl/g brain | μl/min/g brain | ||
| Control | 4 | 56.9 ± 5.66 | 11.8 ± 0.947 |
| Diabetes | 5 | 37.5 ± 7.43*** | 6.90 ± 1.37*** |
↵*** p < 0.001 from the control group by unpaired Student's t test.