Tabular summary of liquid chromatography-ES/MS results for monkey and human urine (0- to 24-h collection, monkey dose: 12 mg/kg; human dose: 400 mg)
Namea | Length | Sequence | Charge State | m/z | Molecular Mass Expected | Molecular Mass Observed | Δ MS | |
|---|---|---|---|---|---|---|---|---|
| Da | ||||||||
| ISIS 301012 | 20 | GCCTCAGTCTGCTTCGCACC | -4 | 1793.1 | 7176.1 | 7176.4 | 0.3 | |
| A | 14 | GTCTGCTTCGCACC | -3 | 1616.8 | 4853.7 | 4853.1 | -0.6 | |
| B | 13 | TCTGCTTCGCACC | -3 | 1501.6 | 4507.7 | 4508.4 | 0.7 | |
| C | 11 | TGCTTCGCACC | -3 | 1288.5 | 3868.6 | 3868.2 | -0.4 | |
| D | 10 | P(S)-GCTTCGCACC | -3 | 1208.3 | 3628.5 | 3628.8 | 0.3 | |
| E | 10 | GCTTCGCACC | -3 | 1181.7 | 3548.6 | 3548.4 | -0.2 | |
| F | 10 | GCCTCAGTCT | -3 | 1182.1 | 3549.6 | 3549.9 | 0.3 | |
| G | 9 | GCCTCAGTC | -3 | 1075.4 | 3229.5 | 3228.8 | -0.7 | |
| H | 8 | GCCTCAGT | -3 | 968.9 | 2909.5 | 2910 | 0.5 | |
| I | 8 | TTCGCACC | -3 | 960.5 | 2883.5 | 2883.6 | 0.1 | |
| J | 7 | GCCTCAG | -2 | 1293.5 | 2589.5 | 2589 | -0.5 | |
↵ a Refer to Fig. 10 for peak identifications.