CP-320626-Related Molecules | Observed in Vitro IC50a | Predicted Catalyst Fast-Fit IC50a | |
---|---|---|---|
μM | |||
1 | 6 | 43 | |
2 | 22 | 91 | |
3 | >30 | 72 | |
4 | >30 | 79 | |
5 | 3.5 | 0.91 | |
6 | >10 | 91 | |
7 | >10 | 6 | |
8 | >10 | 90 | |
9 | >10 | 90 | |
10 | >10 | 97 | |
11 | >10 | 52 | |
12 | >10 | 5.8 | |
13 | >10 | 92 | |
14 | >10 | 30 | |
15 | >10 | 91 | |
16 | 20 | 91 | |
17 | 50 | 95 | |
18 | >30 | 95 | |
19 | >30 | 90 | |
20 | 14 | 92 | |
21 | 5 | 5.2 | |
22 | >30 | 79 | |
23 | >30 | 42 | |
24 | >30 | 90 | |
25 | >10 | 95 | |
26 | >10 | 93 | |
27 | >10 | 60 | |
28 | >10 | 93 | |
29 | >10 | 91 | |
30 | >10 | 91 | |
31 | >10 | 63 | |
32 | >10 | 39 | |
33 | >10 | 14 | |
34 | >10 | 92 | |
35 | 1.2 | 4.8 | |
36 | 5.7 | 8.1 | |
37 | 6.0 | 43 | |
38 | 28 | 1.9 | |
39 | >200 | 1.9 | |
40 | >10 | 26 | |
41 | >10 | 120 | |
42 | >10 | 170 | |
43 | >10 | 29 | |
44 | >10 | 0.46 | |
45 | >10 | 0.51 | |
46 | >30 | 0.39 | |
47 | >30 | 0.41 | |
48 | 0.7 | 0.43 |
↵ a Experimental data are the average of triplicate determinations.