TABLE 3

Allelic frequencies of BCRP variants identified in Koreans ^a

SNP No.	SNP and Position^b	Position Relative to Transcription Start Site	Location	Effect	N	Allelic Frequency
						%
1	-20296A>G	-1379	Promoter		92	13
2	-19855C>T	-938	Promoter		92	0.5
3	-19605A>G	-688	Promoter		92	0.5
4	-19031C>T	-114	Promoter		92	1.6
5	-18631C>T	+286	5′UTR		92	2.2
6	34G>A		Exon 2	V12M	275	23
7	238A>G		Intron 2		92	25
8	7430A>G		Intron 3		92	9.8
9	8191C>T		Exon 4	Q126Stop	375	1.9
10	8825C>A		Exon 5	Q141K	275	28
11	21850C>T		Exon 7	P269S	674	0.2
12	26297G>A		Exon 9		92	1.1
13	38485A>G		Intron 11		92	24
14	40086insA		Intron 12		92	0.5
15	40110G>T		Intron 12		92	22
16	42288C>T		Intron 13		92	67.4
17	42313T>G		Intron 13		92	2.2
18	44072C>T		Intron 13		92	23.4
19	44997A>G		Intron 14		92	49.5
20	45235C>T		Intron 15		92	20.1

↵ a The reference sequence used has GenBank accession no. AC084732.
↵ b Position is indicated with respect to the start codon (ATG) of the BCRP gene; the A in the ATG triplet is designated as +1, and the next base toward the 5′-end is designated as -1.