TABLE 1

Interday variation of % remaining of ethynylestradiol (50 μM) as a MBI-positive reference and ketoconazole (100 nM) as a MBI-negative reference in the automated CYP3A MBI screening using each substrate

The interday data were obtained from the average of the % remaining data from several different studies in duplicate on three different days.

Midazolam

Nifedipine

Testosterone

Ketoconazole
Ketoconazole