TABLE 3

CBR1 gene variants and the resulting 9 most frequent haplotypes determined by sequencing of 57 DNA samples

Bonferroni-corrected significance level for compliance with Hardy-Weinberg equilibrium (χ2 test) was set at <0.005. Bold print indicates differences in comparison with the haplotype H1.


SNP No.

1

2

3

4

5

6

7

8

9

10

11
rs No. N.A. 2239859 1005696 1005695 2835265 2835266 20572 2230192 9024 998384 998383
B (= minor) allele freq. 0.03 0.44 0.49 0.43 0.18 0.03 0.18 0.01 0.21 0.35 0.35
Genotypes AA, AB, BB 55, 1, 1 24, 16, 17 18, 22, 17 19, 27, 11 41, 11, 5 54, 3, 0 41, 11, 5 56, 1, 0 38, 14, 5 25, 24, 8 25, 24, 8
χ2 <0.001 0.005 0.23 0.97 0.03 0.98 0.03 1 0.14 0.85 0.85
Haplotypes (frequency)
    H1 (25.4%) T T G C G C G G G C
    H2 (22.3%) G G C C G C G G C G
    H3 (13.5%) T T G T G T G A G C
    H4 (5.1%) G G C C G C G G G C
    H5 (4.8%) T G C C G C G G C G
    H6 (3.1%) G G G C G C G G G C
    H7 (2.8%) T G G C G C G G G C
    H8 (2.6%) G G C C A C G G G C
    H9 (2.5%)

G
T
G
C
G
C
G
G
G
C
  • N.A., not available.