TABLE 3
F2 values and -fold induction at highest concentration tested (given in parenthesis) for induction of CYP2C8, CYP2C9, and CYP2C19 mRNA in HepaRG cells treated with rifampicin F2 is the concentration resulting in a 2-fold increase of baseline mRNA levels. Values are mean ± S.D. of three separate batches of differentiated HepaRG cells.