TABLE 1

Toxicokinetics of Bmim-Cl after i.v. (5 mg/kg) or oral (50 mg/kg) administration to male F-344 rats

n = 4 per dosing route.

	Dose	AUC	t_1/2α	t_1/2β	CL_b	V_ss	C_max	T_max	F
	μg	minμg/ml*	min	h	ml/min	ml	μg/ml	min	%
i.v.	1047	141.3	13.0	1.4	7.4	618.2
Oral	8756	733.3	30.0	1.3	11.9		3.6	67.0	62.1