TABLE 3

Dose recovered in 72 h after oral administration of Bmim-Cl to male F-344 rats (n = 4) or female B6C3F1 mice (n = 10)

Data are presented as mean ± S.D.



Dose Recovered
Rats
Mice: 50 mg/kg

0.5 mg/kg
5 mg/kg
50 mg/kg
%
Feces 21.4 ± 1.8 19.4 ± 1.7 28.2 ± 3.1 18.1 ± 5.8
Urine 77.5 ± 6.4 77.0 ± 3.1 72.3 ± 6.2 65.0 ± 12.0
Total recovery
98.9 ± 4.8
96.4 ± 4.2
100.6 ± 5.6
83.3 ± 13.6