Dose recovered at 24 h after the final dose following one or five serial daily oral administrations of Bmim-Cl (50 mg/kg/day) to male F-344 rats
Data are presented as mean ± S.D.; n = 4 per treatment group.
Dose Recovered | |||
|---|---|---|---|
| One Administration | Five Administrations | ||
| % | |||
| Feces | 29.9 ± 1.3 | 25.5 ± 5.1 | |
| Urine | 56.3 ± 3.2 | 61.6 ± 2.4 | |
| Blood | 0.1 ± 0 | 0 ± 0 | |
| Tissues | 5.3 ± 2.4 | 1.1 ± 0.2 | |
| Total recovery | 91.5 ± 2.3 | 88.2 ± 3.9 | |