TABLE 2

Demographics of subjects participating in drug interaction study (n = 21) Data are presented as median (range), except for CYP2C9*3/*3 genotype group in which individual data are presented. No significant differences among the CYP2C9 genotype groups, CYP2C9*1/*1, CYP2C9*1/*3, and CYP2C9*3/*3, were noted with respect to age [F(2,18) = 0.95, P = 0.41], body weight [F(2,18) = 1.38, P = 0.28)], height [F(2,18) = 0.48, P = 0.63], or creatinine concentrations [F(2,18) = 1.2, P = 0.32].


Demographics

CYP2C9*1/*1

CYP2C9*1/*3

CYP2C9*3/*3
No. subjects 11 8 2
Age (years) 25 (19–36) 23 (19–28) (25, 29)
Gender (male/female) 4/7 3/5 2/0
Body weight (kg) 73.7 (51–108) 66.9 (49–84) (77, 85)
Height (cm) 166 (154–193) 167 (160–189) (177, 179)
Creatinine concentration
0.87 (0.7–1.27)
0.86 (0.76–1.03)
(1, 1.1)