Reactive P450 phenotyping of drugs
Drug | Relative Contribution (fm) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CYP1A2 | CYP2C9 | CYP2C19 | CYP2D6 | CYP3A4 | |||||
| % | |||||||||
| Budesonide | 8 | 2 | 0 | 0 | 79 | ||||
| Buprenorphine | 7 | 10 | 0 | 1 | 77 | ||||
| Docetaxel | 12 | 0 | 0 | 18 | 70 | ||||
| Loratadine | 16 | 18 | 0 | 24 | 41 | ||||
| Methylprednisolone | 0 | 0 | 10 | 31 | 59 | ||||
| Sirolimus | 0 | 15 | 0 | 0 | 85 | ||||
| Tacrolimus | 0 | 8 | 0 | 1 | 47 | ||||
fm, relative contributions of the P450 toward the metabolism of drug (%)