Demographic data of human hepatocytes used in the study
Hepatocyte Batch | Sex | Age | Ethnicity | Smoker | Alcohol | Medical History/Medications | Use in Present Study |
|---|---|---|---|---|---|---|---|
| 1 | M | 42 | AA | Yes | Yes | None | Metabolite formation, mRNA |
| 2 | M | 31 | C | No | Yes | Depression, antidepressants | Metabolite formation |
| 3 | F | 56 | AA | Yes | Yes | Diabetes, hypertension, vascular disease | Metabolite formation |
| 4 | F | 45 | C | Yes | Yes | Hypertension, kidney stones | mRNA |
| 5 | F | 54 | C | No | No | Diabetes, hypertension, arthritis, kidney disease | mRNA |
| 6 | M | 47 | C | Yes | N.I. | Diabetes | Substrate depletion |
| 7 | F | 60 | C | No | Yes | Antidepressants | Substrate depletion |
| 8 | M | 55 | AA | No | N.I. | Hypertension | Substrate depletion |
N.I., no information; M, male; F, female