TABLE 3

The bioavailability of ximelagatran and melagatran determined in the VP, VH, and VF after enteral administration of 200 mg of ximelagatran alone (TI; n = 6 pigs) or in combination with 250 mg of erythromycin (TII; n = 6 pigs) The bioavailability of melagatran was calculated based on melagatran AUC following enteral administration of ximelagatran and i.v. administration of melagatran (see eq. 7). The values are presented as mean and S.D.