SA | SB | ISA | ISB | SC | SD | ||
---|---|---|---|---|---|---|---|
Healthy | Cmax (ng/ml) | 37 (23, 61) | 106 (63, 177) | 71 (32, 157) | 41 (21, 80) | 37 (18, 76) | 12 (2, 64) |
AUC0-24h (ng · h/ml) | 256 (118, 557) | 617 (327, 1164) | 491 (243, 993) | 251 (145, 436) | 355 (169, 745) | 51 (3, 807) | |
Noncirrhotic | Cmax (ng/ml) | 73 (19, 282) | 269 (73, 995) | 131 (40, 422) | 76 (21, 274) | 144 (49, 423) | 39 (12, 131) |
AUC0-24h (ng · h/ml) | 301 (100, 901) | 1195 (374, 3823) | 858 (282, 2610) | 494 (154, 1588) | 1699 (633, 4564)* | 228 (82, 634) | |
Cirrhotic | Cmax (ng/ml) | 151 (71, 319)* | 551 (309, 982)* | 339 (160, 720)* | 193 (110, 338)* | 147 (68, 318)* | 75 (33, 171)* |
AUC0-24h (ng · h/ml) | 685 (265, 1776)* | 2899 (1082, 7767)* | 2231 (641, 7760)* | 1254 (478, 3287)* | 1841 (802, 4226)* | 507 (167, 1542)* | |
NAFLD | Cmax (ng/ml) | 124 (56, 278)* | 430 (215, 860)* | 216 (96, 485) | 137 (55, 343)* | 190 (100, 361)* | 68 (43, 108)* |
| AUC0-24h (ng · h/ml) | 521 (342, 795) | 1720 (943, 3137) | 1279 (690, 2371) | 706 (406, 1230) | 2043 (1170, 3566)* | 352 (252, 493) |
↵* p ≤ 0.02, comparisons with the healthy cohort.