TABLE 3

Average (S.D., if n ≥ 3) baseline SUV and Kp values over 60 min in cerebellum for the studied radiotracers



[11C]Verapamil

[11C]GR205171

[18F]Altanserin

SUV
Kp
SUV
Kp
SUV
Kp
Rat 0.21 (0.05) 1.13 (0.36) 0.32 (0.05) 3.45 (0.52) 0.32 (0.11)a 0.23 (0.10)a
Guinea pig 0.14 (0.02) 0.65 (0.02) 0.20 (0.05) 2.13 (0.83)
Minipig 1.20 (0.14) 2.08 (0.28)
Monkey 0.40b 4.61b 1.57 (0.36) 9.62 (3.93)
Humanb


2.11 (0.84)c
29.8 (7.0)c
0.90 (0.22)d
1.04 (0.49)d
  • a Ex vivo studies; values at 60 min after radiotracer administration.

  • b One animal.

  • c Syvänen (2003).

  • d Liptrot et al. (2004).