TABLE 6

Summary of TEER, Papp values (× 10–6 cm/s), and efflux ratios for E3S in shRNA vector control-transduced cells



Days in Culture

10
15
21
25
TEER (Ω · cm2, n = 6) 269 386 513 507
Papp, E3S A to B 0.81 0.69 0.55 0.44
Papp, E3S B to A 15.1 16.94 15.57 10.78
Efflux ratio [Papp(B-A/A-B)]
18.65
24.59
28.39
24.59
  • A, apical; B, basolateral.