TABLE 5

Half-lives of human CYP3A4

The half-lives of human CYP3A4 mRNA and proteins were summarized from previous reports.




Half-Life

Ref.a
h
CYP3A4 mRNA 10 37
CYP3A4 protein 17: no decay 42
CYP3A4 protein 85 ± 65 43
CYP3A4 protein 36-50 44
CYP3A4 protein
20-146
45
  • a See Supplemental Data Appendix reference.