TABLE 3

Phenytoin and torsemide binding affinities and capacities

Drug	Parameter	IFABP	BSA
Phenytoin	K _d1	0.16	0.08
	K _d2	4.7	3.8
	C₁^a	19.9	15.7
	C₂^a	11.8	7.4
Torsemide	K _d1	0.79	0.89
	K _d2	N.A.^b	14.7
	C₁^a	17.0	13.1
	C₂^a	N.A.^b	50.5

K_d, μM; C, % ANS displacement; N.A., not applicable.
↵ a C (capacity) was assessed as the maximal percentage capacity of the substrate to displace ANS from the protein.
↵ b Experimental data for torsemide binding to IFABP were best described by a single binding mode equation.