TABLE 4

Summary of estimates of turnover half-lives for cytochrome P450 enzymes in humans ( Yang et al., 2008 )

Enzyme	Range of t_1/2 Values
	Estimated from in Vitro Data	Estimated from in Vivo Data
	hr
CYP1A2	36-51	39-105
CYP2B6	32	No data
CYP2C8	23	No data
CYP2C9	104	No data
CYP2C19	26	No data
CYP2D6	70	51
CYP2E1	27	50-60
CYP3A4	26-79	36-140