TABLE 1

Reported IDT and the maximum daily doses of tested drugs

Drug IDT RiskToxicityMaximum Daily Dose
mg
Safe
    Flufenamic acid750
    Gemfibrozil1200
    Levofloxacin750
    Meclofenamate400
    Montelukast10
    Repaglinide16
    Telmisartan80
Warning
    DiclofenacAnaphylaxis, DILI, SJS150
    FurosemideNeutropenia, thrombocytopenia80
    IbuprofenAnaphylaxis, SJS3200
    IndomethacinAnaphylaxis, SJS200
    Mefenamic acidAnaphylaxis, SJS1250
    NaproxenAnaphylaxis, SJS1000
    ProbenecidAnaphylaxis1000
    TolmetinAnaphylaxis, DILI, SJS1800
Withdrawn
    BenoxaprofenDILI1200
    FenclofenacDILI1800
    IbufenacDILI4000
    ZomepiracAnaphylaxis600
  • DILI, drug-induced liver injury; SJS, Stevens-Johnson syndrome.