Half-lives of AGs in KPB, HSA solution, and human plasma
Data are presented as the mean ± S.D.
| No. | AG | Half-Life | ||
|---|---|---|---|---|
| KPB | HSA | Human Plasma | ||
| h | ||||
| 1 | Flufenamic acid AG | 7.2 ± 0.6 | 7.7 ± 1.1 | 4.4 ± 0.6 |
| 2 | Gemfibrozil AG | 71.4 ± 7.1 | 7.6 ± 0.8 | 1.7 ± 0.1 |
| 3 | Levofloxacin AG | 16.1 ± 2.3 | 16.3 ± 3.8 | 3.1 ± 0.2 |
| 4 | Meclofenamate AG | 28.1 ± 1.6 | 16.6 ± 0.9 | 3.0 ± 0.2 |
| 5 | Montelukast AG | 37.5 ± 5.9 | 21.8 ± 1.0 | 1.7 ± 0.3 |
| 6 | Repaglinide AG | 11.5 ± 1.0 | 7.0 ± 0.2 | 7.0 ± 0.1 |
| 7 | Telmisartan AG | 45.6 ± 5.5 | 111.8 ± 14.0 | 11.7 ± 1.2 |
| 8 | Diclofenac AG | 0.7 ± 0.0 | 0.2 ± 0.0 | 0.1 ± 0.0 |
| 9 | Furosemide AG | 3.2 ± 0.0 | 7.2 ± 0.3 | 3.7 ± 0.2 |
| 10 | Ibuprofen AG | 2.7 ± 0.1 | 1.3 ± 0.0 | 0.8 ± 0.1 |
| 11 | Indomethacin AG | 1.7 ± 0.1 | 0.6 ± 0.0 | 0.2 ± 0.0 |
| 12 | Mefenamic acid AG | 17.0 ± 0.5 | 51.3 ± 6.2 | 5.8 ± 1.1 |
| 13 | R-Naproxen AG | 1.1 ± 0.0 | 1.0 ± 0.1 | 0.3 ± 0.1 |
| 14 | S-Naproxen AG | 2.2 ± 0.1 | 0.3 ± 0.0 | 0.2 ± 0.0 |
| 15 | Probenecid AG | 0.3 ± 0.0 | 0.8 ± 0.0 | 0.2 ± 0.0 |
| 16 | Tolmetin AG | 0.4 ± 0.0 | 0.5 ± 0.0 | 0.2 ± 0.0 |
| 17 | R-Benoxaprofen AG | 0.7 ± 0.0 | 0.8 ± 0.0 | 0.1 ± 0.0 |
| 18 | S-Benoxaprofen AG | 1.4 ± 0.1 | 1.8 ± 0.0 | 0.7 ± 0.1 |
| 19 | Fenclofenac AG | 1.7 ± 0.1 | 0.9 ± 0.2 | 0.8 ± 0.1 |
| 20 | Ibufenac AG | 0.8 ± 0.0 | 0.6 ± 0.0 | 0.3 ± 0.0 |
| 21 | Zomepirac AG | 0.4 ± 0.0 | 0.2 ± 0.0 | 0.1 ± 0.0 |