TABLE 1

Sex differences in UGT2B gene expression in human liver

Gene2−ΔCTap valueb
mRNA Expression MenmRNA Expression Women
n = 62n = 41
UGT2B45.14 ± 0.249.90 ± 2.140.074
UGT2B71.16 ± 0.051.14 ± 0.070.866
UGT2B102.28 ± 0.112.68 ± 0.260.573
UGT2B110.014 ± 0.0010.037 ± 0.0210.339
UGT2B153.71 ± 0.553.35 ± 0.390.178
UGT2B170.424 ± 0.0570.119 ± 0.0290.007
UGT2B280.006 ± 0.0010.126 ± 0.1190.856
  • a Gene expression values are presented as means ± S.E. of each UGT mRNA relative to PPIA mRNA as 2−ΔCT.

  • b The Mann-Whitney test was used to determine statistical significance of expression of UGT2B genes between sexes.