Kinetic parameters of MMF hydrolysis in vitro in human blood fraction
| Sex | Plasma | Erythrocyte | Whole Blood | ||||
|---|---|---|---|---|---|---|---|
| kel | t1/2 | kel | t1/2 | kel | t1/2 | ||
| h−1 | h | h−1 | h | h−1 | h | ||
| HB-1 | M | 0.045 | 15.4 | 0.31 | 2.25 | 0.22 | 3.19 |
| HB-2 | F | 0.020 | 34.7 | 0.55 | 1.26 | 0.17 | 4.03 |
| HB-3 | M | 0.061 | 11.3 | 0.46 | 1.51 | 0.43 | 1.62 |
| HB-4 | F | 0.058 | 12.0 | 0.59 | 1.17 | 0.18 | 3.79 |
| HB-5 | F | 0.062 | 11.3 | 0.41 | 1.71 | 0.21 | 3.38 |
| Average | 0.051 | 15.1 | 0.46 | 1.58 | 0.24 | 3.20 | |
| S.D. | 0.015 | 6.1 | 0.11 | 0.43 | 0.11 | 0.94 | |
M, male; F, female.