TABLE 3

Summary of mRNA expression results in the present study and in the literature

Present Study (db/db Mice)Literature
10-Week-Old*25-Week-Olddb/db (10-Week-Old)ob/ob (8-Week-Old)References
Cyp2b10Yoshinari et al., 2006; Cheng et al., 2008
Cyp2c29N.D.Yoshinari et al., 2006
Cyp3a11Yoshinari et al., 2006; Cheng et al., 2008
Cyp 2e1↑↓Leclercq et al., 2000; Yoshinari et al., 2006; Cheng et al., 2008
Cyp4a10N.D.Yoshinari et al., 2006
PXRN.D.Yoshinari et al., 2006
CARN.D.Yoshinari et al., 2006
slco1a1N.D.Cheng et al., 2008
slco1a4N.D.Cheng et al., 2008
slco1b2N.D.Cheng et al., 2008
abcb1bN.D.N.D.
abcc2N.D.Cheng et al., 2008
abcg2N.D.Cheng et al., 2008
• N.D., no data available; ↔, no change; ↑, increased expression; ↓, decreased expression.

• * Compared with the 25-week-old controls.