Effect of multiple and single doses of ERY treatment on uncomplexed P450, complexed P450, and total P450 protein content
Values are presented as mean ± S.D.
| Uncomplexed P450 | Complexed P450 | Total P450 | p Value* | |
|---|---|---|---|---|
| nmol/mg protein | ||||
| Control | 0.45 ± 0.08 | N.D. | 0.49 ± 0.08 | NA |
| Multiple dose of ERY | 0.42 ± 0.07 | 0.31 ± 0.11 | 0.71 ± 0.18 | 0.18 |
| 1 Day after | 0.47 ± 0.08 | 0.17 ± 0.07 | 0.67 ± 0.11 | 0.13 |
| 2 Days after | 0.57 ± 0.29 | 0.09 ± 0.13 | 0.75 ± 0.38 | 0.15 |
| 3 Days after | 0.46 ± 0.04 | 0.05 ± 0.03 | 0.58 ± 0.03 | 0.21 |
| Single dose of ERY | 0.49 ± 0.03 | N.D. | 0.52 ± 0.03 | 0.32 |
N.D., not detected; NA, not applicable.
↵* p value was calculated for total P450.