Some physical chemical properties of 16 marketed drugs
| Compounds | Molecular Weight | PSA | cLogP | Number of Hydrogen Acceptors | Number of Hydrogen Donors | Number of Hydrogen Bond Acceptors and Donors |
|---|---|---|---|---|---|---|
| Type I | ||||||
| Buspirone | 386 | 70 | 1.4 | 6 | 0 | 6 |
| Clozapine | 327 | 31 | 3.5 | 4 | 1 | 5 |
| Diclofenac | 296 | 49 | 4.4 | 3 | 2 | 5 |
| Gemfibrozil | 250 | 47 | 4.2 | 3 | 1 | 4 |
| Imipramine | 280 | 6 | 4.4 | 2 | 0 | 2 |
| Metoprolol | 267 | 51 | 1.8 | 4 | 2 | 6 |
| Propafenone | 341 | 59 | 3.7 | 4 | 2 | 6 |
| Tolbutamide | 270 | 84 | 2.3 | 3 | 2 | 5 |
| Verapamil | 455 | 64 | 5.5 | 6 | 0 | 6 |
| Type II | ||||||
| Indomethacin | 358 | 69 | 4.2 | 4 | 1 | 5 |
| Prazosin | 383 | 107 | 1.5 | 7 | 1 | 8 |
| Ritonavir | 721 | 202 | 5.0 | 7 | 4 | 11 |
| Type III | ||||||
| Bosentan | 552 | 154 | 3.9 | 10 | 2 | 12 |
| Cyclosporine | 1203 | 279 | 4.3 | 12 | 5 | 17 |
| Montelukast | 586 | 96 | 8.3 | 5 | 2 | 7 |
| Troglitazone | 442 | 111 | 5.8 | 6 | 2 | 7 |