TABLE 4

Potential N-glycosylation sites in baboon, human, and monkey UGT2B enzymes

Comparison of potential N-glycosylation sites in the primary structures of bab (baboon, Papio anubis), h (human), and mon (cynomolgus monkey, Macaca fascicularis) UGT2B enzymes. The sequences for human and monkey UGT2B genes were obtained from the GenBank. Multiple alignments of deduced UGT2B protein amino acid sequences were aligned using the MEGA4.0 software suite. Amino acid sequences were compared, and the potential N-glycosylation sites were identified and tabulated.

Mammalian UGTNumber of Potential N-Glycosylation SitesAmino Acid Position and Sequence of Potential N-Glycosylation Sites
h2B41315-NTS
bab2B41268-NPS315-NMS
bab2B42268-NPS315-NMS
mon2B19268-NPS315-NMS
mon2B30268-NPS315-NMS
h2B7367-NNS68-NSS315-NMT
bab2B39267-NNS68-NSS
bab2B40267-NNS68-NSS
bab2B44267-NNS68-NSS
bab2B45267-NNS68-NSS
bab2B46267-NNS68-NSS
mon2B39267-NNS68-NSS
mon2B18267-NNS68-NSS
mon2B23267-NNS68-NSS
h2B15365-NAS316-NMS483-NLT
h2B17365-NAS316-NMS483-NLT
bab2B43465-NDS103-NST316-NMS483-NLT
mon2B20465-NDS103-NST316-NMS483-NLT