TABLE 2

Summary parameters describing the kinetics of EE2-Sul transport

	K_m or K_m1	V_max or V_max1	K_m2	V_max2	P_dif
	μM	pmol/min/mg	μM	pmol/min/mg	μl/min/mg
Human Hepatocytes^{^a}	0.22 ± 0.05	190 ± 42	15.5 ± 7.0	2350 ± 686	36.5
OATP1B1^{^a}	0.087 ± 0.018	2.42 ± 0.32	141 ± 30	152 ± 22
OATP2B1^{^a}	10.7 ± 2.3	110 ± 7
NTCP^{^a}	2.6 ± 0.5	17.7 ± 1.2
OAT3	21.1 ± 2.7	67.5 ± 3.5
OAT4	1.6 ± 1.8	27.5 ± 21.4	195 ± 138^{^b}	599 ± 225
BCRP^{^a}	2.9 ± 1.3	25.9 ± 11.7	307 ± 143^{^b}	470 ± 125

↵a Cited from the accompanied manuscript (Han et al., 2010).
↵b The maximal concentration of EE2-Sul in the transport study was 200 μM. Therefore, these values are considered to be estimate only.