TABLE 3

Chemical shift of HKI-272 and HKI-272-lysine adduct

HKI-272			HKI-272-Lysine
Atom	¹H δ	¹³C δ	Atom	¹H δ	¹³C δ
2		156.11	2		156.11
3	7.60	121.26	3	7.6	121.37
4	7.89	137.03	4	7.9	137.05
5	7.38	123.00	5	7.39	122.99
6	8.61	148.93	6	8.62	148.98
7	5.29	71.01	7	5.29	70.99
9		151.03	9		150.51
10		121.46	10		121.31
11	7.41	125.73	11	7.42	125.29
12		133.86	12		134.55
13	7.22	124.04	13	7.21	123.49
14	7.27	114.13	14	7.25	114.18
17		147.57	17		147.22
18		87.07	18		87.50
19	8.48	152.13	19	8.47	151.71
21		150.51	21		150.26
22	7.4	108.49	22	7.38	108.25
23		153.15	23		152.64
24		127.59	24		128.14
25	8.97	114.96	25	8.98	113.62
26		112.95	26		113.58
27		117.33	27		117.21
30	4.31	64.32	30	4.32	64.37
31	1.47	14.05	31	1.47	14.25
33		163.67	33	2.29, 2.73	37.98
35	6.61	Not observed	35	2.29	37.82
36	6.76	Not observed	36	3.02	51.65
37	3.11	59.29	37	2.18, 2.42	62.11
39, 40	2.20	44.85	39, 40	2.17	45.31
			42	2.60, 2.71	45.81
			43	1.49	29.26
			44	1.40	22.72
			45	1.62, 1.75	30.74
			46	3.14	53.86