TABLE 3

Summary of pharmacokinetics of CJ-13,610 in healthy fasted male subjects after single oral doses administered as solution

DoseAUC0–∞aCmaxaTmaxt1/2
ngh/mlng/mlh
1 mgN.C.2.1 (0.6)6.8 (3.0)N.C.
3 mg249 (73)11 (3)5.0 (3.4)14.8 (2.0)
10 mg783 (279)34 (10)4.5 (1.0)16.2 (2.8)
30 mg1970 (220)144 (34)1.8 (1.5)13.4 (2.1)
100 mg6240 (2520)684 (263)1.5 (0.6)13.1 (2.9)
300 mg19,700 (4000)2110 (1000)3.5 (0.6)14.6 (0.9)
  • N.C., not calculated because of insufficient data.

  • a Mean (S.D.) are geometric for AUC and Cmax.