List of genes that were exclusively up-regulated in the spleen of female Gstm1-null mice after DCNB treatment for 14 days
Genes whose expression levels increased in the Gstm1-null mice (|expression ratio to control| >1.4) but not in the wild-type mice (|expression ratio to control| < 1.4) after DCNB treatment are extracted. In the table, genes whose increasing ratio between Gstm1-null and wild-type mice (Gstm1-null/wild-type) exhibited a value greater than 2.5 are listed. Expression levels of underlined genes were also measured by quantitative RT-PCR.
| Affymetrix No. | Gene Symbol | Entrez Gene | DCNB/Control | Gstm1-Null/Wild-Type | Gene Title | |
|---|---|---|---|---|---|---|
| Wild-Type | Gstm1-Null | |||||
| 1449366_at | Mmp8 | 17394 | 0.93 | 7.46 | 8.0 | Matrix metallopeptidase 8 |
| 1442801_x_at | Tm7sf3 | 67623 | 1.23 | 9.19 | 7.5 | Transmembrane 7 superfamily member 3 |
| 1452827_at | 1500009C09Rik | 76505 | 1.00 | 6.50 | 6.5 | RIKEN cDNA 1500009C09 gene |
| 1434046_at | AA467197 | 433470 | 0.93 | 5.66 | 6.1 | Expressed sequence AA467197 |
| 1419764_at | Chi3l3 (Ym1) | 12655 | 0.93 | 4.92 | 5.3 | Chitinase 3-like 3 |
| 1427747_a_at | Lcn2 | 16819 | 1.07 | 4.92 | 4.6 | Lipocalin 2 |
| 1427498_a_at | Spag5 | 54141 | 1.07 | 4.59 | 4.3 | Sperm associated antigen 5 |
| 1434484_at | 1100001G20Rik | 66107 | 1.07 | 4.29 | 4.0 | RIKEN cDNA 1100001G20 gene |
| 1441982_at | Taf7 | 24074 | 1.07 | 4.00 | 3.7 | TAF7 RNA polymerase II, TBP-associated factor |
| 1448756_at | S100a9 | 20202 | 1.00 | 3.73 | 3.7 | S100 calcium binding protein A9 (calgranulin B) |
| 1441864_x_at | Cenpa | 12615 | 0.87 | 3.03 | 3.5 | Centromere protein A |
| 1451537_at | Chi3l1 | 12654 | 1.15 | 3.48 | 3.0 | Chitinase 3-like 1 |
| 1416298_at | Mmp9 | 17395 | 0.87 | 2.64 | 3.0 | Matrix metallopeptidase 9 |
| 1445437_at | Ccdc74a | 72315 | 0.87 | 2.46 | 2.8 | Coiled-coil domain containing 74A |
| 1460271_at | Trem3 | 58218 | 0.93 | 2.64 | 2.8 | Triggering receptor expressed on myeloid cells 3 |
| 1427922_at | 2310061C15Rik | 66531 | 0.87 | 2.30 | 2.6 | RIKEN cDNA 2310061C15 gene |
| 1429566_a_at | Hipk2 | 15258 | 1.32 | 3.48 | 2.6 | Homeodomain interacting protein kinase 2 |
| 1424509_at | Cd177 | 68891 | 1.23 | 3.25 | 2.6 | CD177 antigen |
| 1442339_at | Stfa2l1 | 268885 | 0.93 | 2.46 | 2.6 | Stefin A2 like 1 |
| 1449136_at | Epx | 13861 | 0.76 | 2.00 | 2.6 | Eosinophil peroxidase |
| 1419394_s_at | S100a8 | 20201 | 1.15 | 3.03 | 2.6 | S100 calcium binding protein A8 (calgranulin A) |
| 1420572_at | Ms4a3 | 170813 | 1.15 | 3.03 | 2.6 | Membrane-spanning 4-domains, subfamily A, member 3 |