Modifier | Vmax | Ksub | Kmod | a | c | d | Kinetic Model | R2 |
---|---|---|---|---|---|---|---|---|
pmol/(min per mg of protein) | μM | μM | ||||||
Daidzein | 190 (11) | 81 (6.3) | 6.3 (0.57) | 0.11 (0.032) | 2.6 (0.22) | N.A. | Eq. 3 | 0.96 |
SN-38 | 170 (5.9) | 140 (21) | 24 (5.4) | 0.055 (0.018) | 0.65 (0.028) | 1.0 (0.11) | Eq. 4 | 0.99 |
N.A., not applicable, Ksub and Kmod refer to the binding affinity of the substrate and modifier to the enzyme.